Dragon Pharma PNC-27 10 mg is supplied as a lyophilized powder in a 2 mL vial and contains the experimental peptide PNC-27 at a labeled strength of 10 mg/vial. Product specifications, storage information, and other practical product details are provided below.
10 mg/Vial Strength
Each vial is labeled at 10 mg of PNC-27 peptide.
2 mL Vial
Supplied as a lyophilized powder in a sealed 2 mL vial.
Lyophilized Form
Supplied as a freeze-dried powder for reconstitution with bacteriostatic water or suitable diluent.
Dragon Pharma
Manufactured and packaged under the Dragon Pharma product line.
Product Specifications
Product name
PNC-27 10 mg
Active substance
PNC-27
Labeled strength
10 mg/vial
Container
2 mL vial
Product form
Lyophilized powder
Manufacturer
Dragon Pharma
Related Products
Other research peptides available from Dragon Pharma include Adipotide 10 mg, a peptide investigated for its potential effects on adipose tissue, and AICAR 50 mg, a research compound studied for metabolic pathways. Each has a distinct research profile and mechanism of action.
Science & Research
Understanding PNC-27
PNC-27 is an experimental peptide composed of 32 amino acids. It is a synthetic peptide that combines a portion of the p53 tumor suppressor protein with a cell-penetrating peptide sequence. PNC-27 is being researched for its potential to target cancer cells through a distinct mechanism of action.
1
Fusion Peptide Design
PNC-27 is a fusion peptide consisting of a p53-derived sequence linked to a cell-penetrating peptide for cellular uptake.
2
HDM-2 Targeting
In laboratory studies, PNC-27 has been shown to target HDM-2 proteins on cancer cell membranes, creating pores that lead to cell death.
3
Necrotic Cell Death
Laboratory studies indicate that PNC-27 induces cell death through necrosis rather than apoptosis, a distinct pathway of cell death.
Mechanism of Action
PNC-27 is a synthetic fusion peptide that incorporates a portion of the p53 tumor suppressor protein sequence linked to a cell-penetrating peptide. The p53 protein is known as a key regulator of cellular stress responses and is often inactivated in cancer cells.
In laboratory studies, PNC-27 has been shown to target HDM-2 proteins on cancer cell membranes. The interaction between PNC-27 and HDM-2 is thought to create pores in the cell membrane, leading to necrotic cell death. This proposed mechanism is distinct from apoptosis and represents a different pathway of cell death induction.
Research Context
PNC-27 has been investigated in preclinical research for its potential to selectively target cancer cells. The peptide's design, combining a tumor suppressor-derived sequence with a cell-penetrating peptide, represents an approach to targeted cell death induction.
Dragon Pharma PNC-27 10 mg is supplied as a lyophilized powder in a 2 mL vial at a labeled strength of 10 mg/vial.
Research References
PNC-27 has been the subject of preclinical research investigating its properties and potential applications. Published literature provides information on the compound's mechanism of action.
PNC-27 is an experimental research peptide with limited safety data in humans. As a compound designed to induce cell death through membrane pore formation, its use requires careful consideration of potential physiological effects.
Cellular Effects
PNC-27 is designed to induce necrotic cell death through membrane pore formation. The full scope of effects on different cell types is not fully characterized.
Injection Site Reactions
Reconstituted peptides may cause localized reactions at the injection site. Proper aseptic technique is essential for preparation and administration.
Pregnancy and Breastfeeding
PNC-27 is not indicated for use during pregnancy or breastfeeding. Its effects on fetal development and infant health are not established.
Unknown Risks
As a research compound, the long-term safety profile of PNC-27 is not fully established. Unknown risks may exist.
Conditions That Require Medical Review
Medical advice is particularly important when there is a history of autoimmune conditions, or when taking medications that may interact with cellular signaling pathways.
The product should also be stored securely to prevent accidental access or use by children or other household members.
When to Seek Urgent Medical Help
Seek urgent medical attention for symptoms such as severe allergic reactions, chest pain, sudden shortness of breath, fainting, or signs of a serious adverse reaction.
Tested Sport
PNC-27 is not currently listed on the WADA Prohibited List. However, the use of peptides and research compounds may be subject to specific anti-doping rules depending on the sport and governing body. Current requirements should be checked against the relevant anti-doping rules before competition.
Quick answers about PNC-27 10 mg specifications, storage, shipping, Bitcoin payment and general product information.
What is Dragon Pharma PNC-27 10 mg?
Dragon Pharma PNC-27 10 mg is a lyophilized peptide product containing PNC-27 at a labeled strength of 10 mg per vial. It is supplied in a 2 mL vial as a freeze-dried powder.
What is PNC-27?
PNC-27 is an experimental fusion peptide composed of 32 amino acids. It combines a portion of the p53 tumor suppressor protein with a cell-penetrating peptide. Laboratory studies have investigated its potential to target cancer cells through HDM-2 binding and membrane pore formation.
How is PNC-27 10 mg supplied?
It is supplied as a lyophilized powder in a 2 mL vial. The product must be reconstituted with a suitable diluent such as bacteriostatic water before use in a research setting.
What is the mechanism of action of PNC-27?
PNC-27 is designed to target HDM-2 proteins on cancer cell membranes. In laboratory studies, this interaction creates pores in the membrane, leading to cell death through necrosis rather than apoptosis.
Is PNC-27 10 mg FDA approved?
No. PNC-27 is not FDA-approved for any therapeutic use. It is a research compound intended for laboratory and preclinical research purposes only.
How should PNC-27 10 mg be stored?
Keep the lyophilized powder in its original packaging and protect it from excessive heat, moisture and direct light. Refer to the product label for specific storage directions regarding temperature and shelf life. Once reconstituted, the solution should be used promptly or stored according to the manufacturer's directions.
Does PNC-27 10 mg require refrigeration?
Follow the storage instructions printed on the supplied product. Lyophilized peptides often require refrigeration, but specific storage conditions should be verified from the product label.
How long does PNC-27 10 mg delivery take?
Delivery depends on the warehouse selected for the order. Shipments from the USA Warehouse typically take 4–5 business days after dispatch, while shipments from the International Warehouse typically take 15–20 business days after dispatch. Full delivery and reship information is available on the Shipping Information page.
Can I buy PNC-27 10 mg with Bitcoin?
Yes. Bitcoin and other supported cryptocurrencies are available at checkout for all orders. To buy PNC-27 10 mg with Bitcoin, select Bitcoin as the payment method during checkout and follow the payment instructions provided with the order.
Is Bitcoin payment anonymous?
Bitcoin transactions are recorded on a public blockchain and should not be considered automatically anonymous. Accurate order and delivery information is still required for order processing and shipping.
Is PNC-27 permitted in tested sport?
PNC-27 is not currently listed on the WADA Prohibited List. However, the use of peptides and research compounds may be subject to specific anti-doping rules depending on the sport and governing body. Current requirements should be checked against the relevant anti-doping rules before competition.
Where can I find more information about PNC-27?
Additional information about PNC-27 is available through PubMed and other research literature databases. Direct links are provided in the Science & Research section above.
