

Anastrozole tablets are manufactured by Balkan Pharmaceuticals, Europe in the strengths of 1 mg of Anastrozole. We also have in stock Exedrol (Exemestane) which is also used to treat the same indications.
One tablet of Anastrozole, regardless of the manufacturer, contains 1 mg of the same active substance.
Additional components: povidone, lactose monohydrate, silicon dioxide, microcrystalline cellulose, magnesium stearate, sodium carboxymethyl starch.
Sheath composition: macrogol-4000, hypromellose, titanium dioxide.
White round tablets, covered with a shell, biconvex form, on the cut you can see a white core and a shell.
Antineoplastic, inhibits the synthesis of estrogens.
Pharmacodynamics
This agent is a potent and highly selective non-steroidal aromatase blocker. In postmenopausal women, estradiol is produced by the transformation of androstenedione into the tissues of peripheral organs in estrone with the participation of the aromatase enzyme. Estrone is converted to estradiol.
Lowering the level of estradiol causes a therapeutic effect in female patients suffering from malignant neoplasms of the breast. In postmenopause, the use of 1 mg of Anastrozole per day leads to a drop in the content of estradiol by 80%.
Pharmacokinetics
Absorption of the drug is rapid, the highest concentration in the blood is obtained after two hours with fasting. The half-life period reaches 50 hours. The food slows down the suction speed a little.
It binds to blood proteins by 40%. Metabolized extensively. It is excreted by the kidneys in its original form 72 hours after administration. Metabolites are also excreted mainly by the kidneys.
During the premenopause:
Caution should be used for hypercholesterolemia, osteoporosis, coronary heart disease, impaired liver function, severe renal failure, lactose intolerance, lactase deficiency, malabsorption of glucose or galactose.
Instructions for Anastrozole, instructions for Arimidex and instructions for Arimixyl are fundamentally similar to each other. It is recommended to take the drug inside, swallowing it whole and squeezed with a small amount of water. You should take the drug at the same time of day. Eating does not matter.
Anastrozole is used one tablet per day for a long period of time. If signs of disease progression are detected, the drug should be discontinued. The recommended duration of therapy as an adjuvant is 5 years.
Treatment: there is no specific antidote, and symptomatic treatment is performed. You can induce vomiting if the patient is conscious. Dialysis is allowed. Supportive therapy, monitoring and control of vital systems and organs are recommended.
Clinically significant pharmacological interaction with drug while taking other drugs is absent.
Drugs containing estrogens. inhibits the pharmacological effects of Anastrozole, therefore they should not be taken with Anastrozole.
Keep away from children, store at a temperature of up to 25° C.
3 years.
A number of adverse reactions of the drug may adversely affect the ability to drive a car.
Analogues related to one group: Femara, Letroxyl, Letrozole, Aromasin, Aromadex, Aromaxyl, Exedrol.
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Jan 25, 2018 (12:04)
The anastrozole was to keep estrogen in check and it definitely works NO evidence of high estrogen whatsoever
This source has definitely got all aspects of the entire process from ordering to receiving down to a science. I definitely highly recommend this source!